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Quinolone Resistance in Enterotoxigenic Escherichia coli Causing Diarrhea in Travelers to India in Comparison with Other Geographical Areas

机译:与其他地理区域相比,印度旅客产生的肠毒素致大肠杆菌中的喹诺酮耐药性

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摘要

Enterotoxigenic Escherichia coli isolates were identified as a cause of traveler's diarrhea in 82 of 520 (16%) patients and tested for resistance to seven antimicrobial agents. Thirty patients (36%) needed antimicrobial therapy: 17 (56%) for persistence of symptoms and 13 (44%) for severity of symptoms. Ampicillin, tetracycline, and trimethoprim-sulfamethoxazole resistance was high. Chloramphenicol showed moderate activity, and amoxicillin plus clavulanic acid, nalidixic acid, and ciprofloxacin showed very good activity. Five nalidixic acid-resistant strains were isolated, four from patients visiting India.
机译:520例(16%)患者中有82例肠毒素原性大肠杆菌被认为是旅行者腹泻的原因,并测试了其对7种抗菌药物的耐药性。 30例患者(36%)需要抗微生物治疗:17例患者(56%)持续症状,13例患者(44%)症状严重。氨苄西林,四环素和甲氧苄啶-磺胺甲恶唑的耐药性较高。氯霉素显示中等活性,阿莫西林加克拉维酸,萘啶酸和环丙沙星显示非常好的活性。分离出五种耐萘啶酸的菌株,其中四种来自印度的患者。

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